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P Leif Bergsagel Selected Research

LCL161

1/2022Transplantation of autologous bone marrow pre-loaded ex vivo with oncolytic myxoma virus is efficacious against drug-resistant Vk*MYC mouse myeloma.
12/2016IAP antagonists induce anti-tumor immunity in multiple myeloma.

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P Leif Bergsagel Research Topics

Disease

87Multiple Myeloma
04/2024 - 03/2002
47Neoplasms (Cancer)
05/2024 - 03/2002
6Disease Progression
11/2020 - 12/2015
4Hematologic Neoplasms (Hematological Malignancy)
01/2022 - 10/2012
4Immunoglobulin Light-chain Amyloidosis
01/2022 - 05/2012
4Carcinogenesis
01/2021 - 11/2006
4Waldenstrom Macroglobulinemia (Macroglobulinemia)
09/2017 - 04/2009
3Chromosome Aberrations (Chromosome Abnormalities)
11/2023 - 01/2003
3Amyloidosis
01/2022 - 01/2003
3Trisomy (Trisomies)
01/2020 - 07/2005
3Lymphoma (Lymphomas)
09/2017 - 10/2012
2Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2023 - 11/2020
2Residual Neoplasm
10/2021 - 08/2015
2Testicular Neoplasms (Testicular Cancer)
09/2021 - 04/2007
2Bone Diseases (Bone Disease)
01/2021 - 11/2011
1Chromothripsis
05/2024
1Plasmacytoma
11/2023
1COVID-19
01/2023
1Infections
01/2022
1Obesity
01/2021
1Smoldering Multiple Myeloma
01/2020
1Leprosy (Hansen's Disease)
10/2018

Drug/Important Bio-Agent (IBA)

14Bortezomib (Velcade)FDA Link
01/2022 - 04/2007
12Dexamethasone (Maxidex)FDA LinkGeneric
01/2022 - 10/2007
10Lenalidomide (CC 5013)FDA Link
01/2023 - 10/2007
8Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2022 - 08/2011
7Immunoglobulins (Immunoglobulin)IBA
05/2024 - 03/2002
7Cyclin DIBA
04/2017 - 08/2003
6Proteins (Proteins, Gene)FDA Link
09/2023 - 05/2005
6Cyclin D1IBA
05/2008 - 01/2003
5Phosphotransferases (Kinase)IBA
01/2020 - 07/2002
4NF-kappa B (NF-kB)IBA
05/2024 - 08/2007
4Immunomodulating AgentsIBA
11/2023 - 10/2009
4Proteasome InhibitorsIBA
01/2022 - 01/2011
4pomalidomideIBA
01/2021 - 10/2009
4Immunoglobulin M (IgM)IBA
09/2017 - 09/2005
4DNA (Deoxyribonucleic Acid)IBA
04/2017 - 04/2007
4Thalidomide (Thalomid)FDA Link
04/2015 - 01/2003
3Peptides (Polypeptides)IBA
05/2024 - 01/2016
3Chimeric Antigen ReceptorsIBA
01/2023 - 10/2021
3ixazomibIBA
01/2022 - 11/2016
3Proteasome Endopeptidase Complex (Proteasome)IBA
11/2017 - 01/2011
3Type 3 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 3)IBA
11/2006 - 05/2004
3Cyclin D3IBA
08/2004 - 01/2003
2LCL161IBA
01/2022 - 12/2016
2Immune Checkpoint InhibitorsIBA
01/2022 - 03/2021
2AntigensIBA
09/2021 - 04/2007
2Biomarkers (Surrogate Marker)IBA
03/2021 - 12/2015
2Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
11/2020 - 01/2014
2CytokinesIBA
12/2019 - 01/2018
2carfilzomibIBA
12/2017 - 04/2015
2UbiquitinIBA
11/2017 - 12/2015
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2016 - 04/2009
2ChromatinIBA
10/2015 - 03/2008
2Carrier Proteins (Binding Protein)IBA
07/2014 - 05/2005
2Melphalan (Alkeran)FDA LinkGeneric
01/2014 - 01/2003
2Small Interfering RNA (siRNA)IBA
02/2010 - 11/2006
2PD 173074IBA
11/2006 - 05/2004
1Interleukin-6 (Interleukin 6)IBA
05/2024
1APOBEC-1 DeaminaseIBA
05/2024
1LanosterolIBA
04/2024
1thiamine triphosphorate (TTP)IBA
11/2023
1NIMA-Related KinasesIBA
10/2023
1Drug CombinationsIBA
09/2023
1Immunoglobulin G (IgG)IBA
01/2023
1Circulating Tumor DNAIBA
11/2022
1Complement System Proteins (Complement)IBA
11/2022
1B-Cell Maturation AntigenIBA
01/2022
1Therapeutic UsesIBA
01/2022
1trans-crotonin (CTN)IBA
10/2021
1Bispecific AntibodiesIBA
01/2021
1Programmed Cell Death 1 ReceptorIBA
01/2021
1Acetate-CoA Ligase (Acetyl CoA Synthetase)IBA
01/2021
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2021
1Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA
01/2021
1antineoplaston A10 (A 10)IBA
01/2020
16- amino- N- (3- (4- (4- morpholinyl)pyrido(3',2'- 4,5)furo(3,2- d)pyrimidin- 2- yl)phenyl)- 3- pyridinecarboxamideIBA
01/2020
1APY0201IBA
01/2020
1apilimodIBA
01/2020
1Conditioned Culture MediaIBA
11/2019
1Protein Disulfide-IsomerasesIBA
01/2019
1Interleukin-5 (Interleukin 5)IBA
12/2018
1Interleukin-17 (Interleukin 17)IBA
12/2018
1Blocking AntibodiesIBA
12/2018
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
10/2018
1Clofazimine (Lamprene)FDA Link
10/2018
1PolyaminesIBA
10/2018
1InterleukinsIBA
01/2018
1Interleukin-18 (Interleukin 18)IBA
01/2018
1CB-5083IBA
11/2017
1ATPases Associated with Diverse Cellular ActivitiesIBA
11/2017
1Codon (Codons)IBA
04/2017

Therapy/Procedure

36Therapeutics
11/2023 - 01/2003
8Immunotherapy
01/2023 - 10/2012
4Drug Therapy (Chemotherapy)
01/2023 - 01/2003
4Stem Cell Transplantation
01/2023 - 06/2011
2Precision Medicine
11/2022 - 11/2020
2Cell- and Tissue-Based Therapy (Cell Therapy)
01/2022 - 09/2021
1Radiotherapy
11/2023
1Hematopoietic Stem Cell Transplantation
01/2019